An improved synthesis of the molecule SR 48692 is presented and its use as a neurotensin antagonist biological probe for use in cancer research is described. The preparation includes an number of enhanced chemical conversions and strategies to overcome some of the limiting synthetic transformations in the original chemical route.
[Battilocchio, Claudio; Baxendale, Ian R.; Biava, Mariangela; Kitching, Matthew O.; Ley, Steven V. Organic Process Research and Development, 2012 , vol. 16, # 5 p. 798 - 810]
![6-(2-hydroxyethyl)-5-methyl-2-methylsulfanyl-1H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one,3-methylsulfanyl-1H-1,2,4-triazol-5-amine Structure](https://image.chemsrc.com/caspic/382/50346-47-9.png)
