Role of copper in catalyzing aryl and heteroaryl--Nitrogen (or-oxygen) bond formation under ligand-free and solvent-free conditions

B Basu, S Das, B Mandal

Index: Basu, Basudeb; Das, Sajal; Mandal, Bablee Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2008 , vol. 47, # 11 p. 1701 - 1706

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Citation Number: 5

Abstract

Formation of aryl-or heteroaryl-nitrogen (or-oxygen) bonds under ligand and solvent-free conditions are highly selective to the presence of copper. While bromoarenes undergo CN (or-O) coupling in stoichiometric presence of copper, heteroaryl bromides require only catalytic amounts of copper (I) salts depending on the position of bromo substituents. Such selectivity coupled with ligand and solvent-free protocols appear promising from the ...