Angewandte Chemie. International edition in English 2007-06-01

Selective adsorption of DNA on chiral surfaces: supercoiled or relaxed conformation.

Anton Y Peleg, Jennifer Adams, David L Paterson

Index: Angew. Chem. Int. Ed. Engl. 48(29) , 5282-6, (2009)

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Abstract

The right fit: Plasmid DNA molecules show chirality-dependent interaction with gold surfaces modified by L and D N-isobutyrylcysteine. Relaxed DNA molecules have a stronger interaction and adsorption on the L surface, while their counterparts on the D surface maintain a supercoiled conformation, indicating a weak interaction (see picture).