Organic Letters 2013-09-20

Pd-catalyzed oxidative CH/CH direct coupling of heterocyclic N-oxides.

Wei Liu, Yahui Li, Yue Wang, Chunxiang Kuang

Index: Org. Lett. 15(18) , 4682-5, (2013)

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Abstract

A highly efficient protocol for C-H/C-H cross-coupling has been found to occur between 2-aryl-1,2,3-triazole N-oxides and pyridine N-oxide derivatives. In addition, two homocoupling reactions of 2-substituted 1,2,3-triazole N-oxides and some pyridine N-oxide derivatives were developed. A possible pathway of C-H/C-H direct coupling is discussed.