Journal of Bioscience and Bioengineering 2012-11-01

Production of a new pyridine N-oxide by bioconversion with Cunninghamella echinulata var. elegans.

Jia Zeng, David Gage, Jixun Zhan

Index: J. Biosci. Bioeng. 114(5) , 497-9, (2012)

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Abstract

A new N-oxide was produced from 3-(N-Boc-aminomethyl)-5-bromopyridine by bioconversion with Cunninghamella echinulata var. elegans ATCC 9245, and its structure was established based on the spectral data. The microbial N-oxidation is efficient and highly selective. The substrate was transformed into the product in 7 days.Copyright © 2012 The Society for Biotechnology, Japan. Published by Elsevier B.V. All rights reserved.