Tetrahedron

Recent advances in the synthesis of nicotine and its derivatives

FF Wagner, DL Comins

Index: Comins, Daniel L.; Herrick, James J. Heterocycles, 1987 , vol. 26, # 8 p. 2159 - 2164

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Citation Number: 50

Abstract

(S)-Nicotine (1) is present together with a number of minor alkaloids in tobacco and a wide variety of other plants. Dried leaves of the tobacco plants Nicotiana rustica and N. tabacum contain as much as 2–8% of (S)-nicotine. 1 Interest in the actions of nicotine has remained