Amides by microwave-assisted dehydration of ammonium salts of carboxylic acids

Y Peng, G Song

Index: Peng, Yanqing; Song, Gonghua Organic Preparations and Procedures International, 2002 , vol. 34, # 1 p. 95 - 97

Full Text: HTML

Citation Number: 2

Abstract

The preparation of primary amides is an important reactions in organic chemistry. Reported methods for such conversion include a) direct reaction of acids with ammonia; b) ammonolysis of the corresponding anhydrides or esters and c) reaction of acyl chlorides with gaseous or aqueous ammonia.'The ammonolysis of esters is generally a sluggish reaction unless the esters have good leaving groups.* Litjens and co-workers have ...