Noreen Bannan, Siobhan Rooney, John O'connor
Index: Drug Alcohol Rev. 26(1) , 83-5, (2007)
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The prevalence of zopiclone misuse in clients attending a methadone maintenance programme in Dublin through detection of its degradation product, 2-amino-5-chloropyridine (ACP) on urinalysis is outlined. Urine samples from all 158 clients were tested for the presence of ACP, opiates, benzodiazepines, cocaine, alcohol and cannabis. Of the 37 (23%) clients who tested positive for ACP, 23 (62%) were interviewed. A profile of zopiclone misusers is outlined, including details of demographics, drug history, viral status, recent urinalysis results and opinions on zopiclone. Of the 14 (38%) clients who were not interviewed, information was obtained from their clinical casenotes and documented urinalysis results. The prevalence of zopiclone misuse was reported as 23%. Benzodiazepines were the most popular drug of misuse with zopiclone followed by heroin/opiates. Zopiclone is being misused by drug users in Dublin in the context of many other drugs. Prescribing of zopiclone should be restricted, especially among drug misusers.
Structure | Name/CAS No. | Molecular Formula | Articles |
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2-Amino-5-chloropyridine
CAS:1072-98-6 |
C5H5ClN2 |
Simultaneous determination of zopiclone and its degradation ...
2012-10-15 [J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 907 , 49-55, (2012)] |
Capillary electrophoretic enantioselective determination of ...
2012-06-01 [Electrophoresis 33(11) , 1606-12, (2012)] |
Degradation of zopiclone during storage of spiked and authen...
2013-01-01 [Int. J. Legal Med. 127(1) , 69-76, (2013)] |
Detection of 2-amino-5-chloropyridine in urine as a paramete...
1997-01-01 [J. Anal. Toxicol. 21(3) , 208-12, (1997)] |
Stability tests of zopiclone in whole blood.
2010-07-15 [Forensic Sci. Int. 200(1-3) , 130-5, (2010)] |
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