Nucleosides, Nucleotides & Nucleic Acids 2005-01-01

Synthesis of homo-N-nucleoside with 1,2,4-triazole-3-carboxamide.

Moon Woo Chun, Jin Hee Kim, Myong Jung Kim, Bo Ram Kim, Lak Shin Jeong

Index: Nucleosides Nucleotides Nucleic Acids 24(5-7) , 979-81, (2005)

Full Text: HTML

Abstract

On the basis of potent biological activities of ribavirin and homo-N-nucleosides, a novel homo-N-1,2,4-triazole-3-carboxamide derivative 1 was synthesized starting from 2,3,5-tri-O-benzoylribofuranosyl-1-acetate as a potential antiviral agent.