Journal of Pharmacy and Pharmacology 2002-03-01

A validated high performance liquid chromatographic method for the analysis of Goldenseal.

Wenkui Li, John F Fitzloff

Index: J. Pharm. Pharmacol. 54(3) , 435-9, (2002)

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Abstract

Goldenseal (Hydrastis canadensis L.) has emerged as one of the top ten herbal supplements on the worldwide market. A rapid, simple and validated high performance liquid chromatographic method, with photodiode array detection, has been developed for the analysis of commercial Goldenseal products. Samples were treated by sonication with acidified methanol/water. The method was validated for LOD, LOQ, linearity, reproducibility and recovery with good results.