Structure–activity studies of a series of dipyrazolo [3, 4-b: 3′, 4′-d] pyridin-3-ones binding to the immune regulatory protein B7. 1

NJ Green, J Xiang, J Chen, L Chen, AM Davies…

Index: Bioorganic and Medicinal Chemistry, , vol. 11, # 13 p. 2991 - 3013

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Citation Number: 27

Abstract

... Bioorganic & Medicinal Chemistry. ... Starting from either 25a or 25b and following the same chemistry as depicted in Scheme 1, the 6-phenyl and 6-benzyl dihydrodipyrazolopyridinones 27 and 32 were obtained via the phenyl and benzyl chloropyridine intermediates 26a and ...