Cytotoxic Geranylated Xanthones and O-Alkylated Derivatives of. ALPHA.-Mangostin

LD Ha, PE Hansen, O Vang, F Duus, HD Pham…

Index: Ha, Ly Dieu; Hansen, Poul Erik; Vang, Ole; Duus, Fritz; Pham, Hung Dinh; Nguyen, Lien-Hoa Dieu Chemical and Pharmaceutical Bulletin, 2009 , vol. 57, # 8 p. 830 - 834

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Citation Number: 19

Abstract

Two new geranylated xanthones, 6-O-methylcowanin (4) and oliverixanthone (5), along with five known compounds, cowanin, rubraxanthone, cowaxanthone, cowanol, and β- mangostin, have been isolated from the bark of Garcinia oliveri. For comparison of their biological activities, one mono-and seven di-O-alkylated α-mangostin derivatives were synthesized from α-mangostin. The structures of all compounds were assigned by ...