Antitumor agents. Part 236: Synthesis of water-soluble colchicine derivatives

K Nakagawa-Goto, CX Chen, E Hamel, CC Wu…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 1 p. 235 - 238

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Citation Number: 29

Abstract

... Please enable JavaScript to use all the features on this page. Bioorganic & Medicinal Chemistry Letters. ... [2] and [3] However, the high toxicity of 1 prevents medicinal use as an antitumor agent, although 1 is used for the treatment of gout. ...