e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Synthesis
Synthesis of 2-Aminoindole-3-carboxylic Acid Derivatives by the Copper (I) Iodide Catalyzed Reaction of N-(2-Iodophenyl) formamides with Malononitrile or …
... In order to synthesize 2-aminoindole-3-carbonitrile (3a), 2-iodoaniline was first subjected to the reaction with malononitrile (2a) (2 equiv ... 2001, 2732; 8 Fukamachi S. Konishi H. Kobayashi K. Synthesis 2010, 1593; 9 Petit GR. ... Dattolo G. Cirrincione G. Tetrahedron 2000, 56: 5177. 5 ...