European Journal of Organic Chemistry

Catalytic Enantioselective Oxidation of Bulky Alkyl Aryl Thioethers with H2O2 over Titanium–Salan Catalysts

KP Bryliakov, EP Talsi

Index: Bryliakov, Konstantin P.; Talsi, Evgenii P. European Journal of Organic Chemistry, 2011 , # 24 p. 4693 - 4698

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Citation Number: 14

Abstract

Abstract A simple and efficient catalytic procedure for the oxidation of bulky (preferably aryl benzyl substituted) thioethers with hydrogen peroxide in good to high yields and enantioselectivities (up to 98.5% ee) is reported. The high optical yields are achieved in a tandem stereoconvergent enantioselective oxidation and kinetic resolution process. A reasonable balance between the sulfoxide yield and enantioselectivity could be found by ...