Molecular Diversity 2011-02-01

Synthesis of 5-aryl-1,3-dimethyl-6-(alkyl- or aryl-amino) furo [2,3-d]pyrimidine derivatives by reaction between isocyanides and pyridinecarbaldehydes in the presence of 1,3-dimethylbarbituric acid.

Malek Taher Maghsoodlou, Ghasem Marandi, Nourallah Hazeri, Sayyed Mostafa Habibi-Khorassani, Ali Akbar Mirzaei

Index: Mol. Divers. 15(1) , 227-31, (2011)

Full Text: HTML

Abstract

5-Aryl-6-(alkyl- or aryl-amino)-1,3-dimethylfuro [2,3-d]pyrimidine derivatives were obtained by in situ reaction alkyl or aryl isocyanides and pyridinecarbaldehyde derivatives in the presence of 1,3-dimethylbarbituric acid in dichloromethane without any prior activation or modifications.