Contact Dermatitis 1985-03-01

Contact urticaria from diethyl fumarate.

A Lahti, H I Maibach

Index: Contact Dermatitis 12(3) , 139-40, (1985)

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Abstract

The contact urticariagenic properties of diethyl fumarate were studied using the guinea pig ear swelling assay and by open application on the human upper back skin. Diethyl fumarate caused non-immunologic contact urticaria in both human and guinea pig skin, and the reactions exhibited similar dose dependency and timing of maximal response.