Trichosporon beigelli esterase (TBE): a versatile esterase for the resolution of economically important racemates

S Koul, JL Koul, B Singh, M Kapoor, R Parshad…

Index: Koul, Surrinder; Koul, Jawahir Lal; Singh, Budh; Kapoor, Munish; Parshad, Rajinder; Manhas, Kuldeep S.; Taneja, Subhash C.; Qazi, Ghulam N. Tetrahedron Asymmetry, 2005 , vol. 16, # 15 p. 2575 - 2591

Full Text: HTML

Citation Number: 22

Abstract

A hydrolase producing strain Trichosporon beigelli esterase (TBE) isolated from local cottage cheese in its native form has displayed versatility and high efficacy in the kinetic resolution of a wide range of economically important substrates, which include racemic secondary alcohols, such as 1-(6-methoxy-2-naphthyl) ethanol (E∼ 316), 1-(3, 4- methylenedioxyphenyl) ethanol and pentanol (E∼ 180 and 156 resp.), and alkyl esters of ...