Chelation as a Driving Force in Organic Reactions. IV. 1 Synthesis of α-Nitro Acids by Control of the Carboxylation-Decarboxylation Equilibrium 2

HL Finkbeiner, M Stiles

Index: Finkbeiner,H.L.; Stiles,M. Journal of the American Chemical Society, 1963 , vol. 85, p. 616 - 622

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Citation Number: 129

Abstract

Treatment of primary nitroparaffins with carbon dioxide and magnesium methoxide (magnesium methyl carbonate) leads to magnesium salts of the corresponding a- nitrocarboxylic acids. These salts can be converted easily into the free nitro acids, the esters or the corresponding amino acids. The carboxylation reaction thus serves as a valuable method for synthesizing these compounds. On the basis of the contrasting behavior of ...