... Bioorganic & Medicinal Chemistry Letters. ... a UCB, Medicinal Chemistry, Granta Park, Great Abington ... 8 Compound 1 was considered a promising chemical starting point due to its low molecular weight and resultant high ligand efficiency (0.4164 kcal mol −1 against PI3Kγ). ...
![7-Fluoro-2H-benzo[b][1,4]oxazin-3(4H)-one Structure](https://image.chemsrc.com/caspic/123/103361-99-5.png)
![2-(6-BROMO-2H-BENZO[B][1,4]OXAZIN-4(3H)-YL)-6,6-DIMETHYL-6,7-DIHYDROTHIAZOLO[5,4-C]PYRIDIN-4(5H)-ONE Structure](https://image.chemsrc.com/caspic/129/1000793-42-9.png)
![6,6-dimethyl-2-[6-(1-methylpyrazol-4-yl)-2,3-dihydro-1,4-benzoxazin-4-yl]-5,7-dihydro-[1,3]thiazolo[5,4-c]pyridin-4-one Structure](https://image.chemsrc.com/caspic/412/1000793-52-1.png)
![7-Bromo-2H-benzo[b][1,4]oxazin-3(4H)-one Structure](https://image.chemsrc.com/caspic/361/321436-06-0.png)
![7-Bromo-3,4-dihydro-2H-benzo[b][1,4]oxazine Structure](https://image.chemsrc.com/caspic/035/105679-22-9.png)