Advances in Experimental Medicine and Biology 2000-01-01

Synthesis of taurine analogues from alkenes: preparation of 2-aminocycloalkanesulfonic acids.

F Machetti, M Cacciarini, F Catrambone, F M Cordero, M Frosini, F De Sarlo

Index: Adv. Exp. Med. Biol. 483 , 399-401, (2000)

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Abstract

(+/-)trans 2-Aminocyclohexanesulfonic acid and (+/-)trans 2-aminocyclopentanesulfonic acid were prepared from cyclohexene and cyclopentene respectively by sulfur monochloride addition, followed by oxidation to 2-chlorosulfonic acid and substitution of chlorine.