Synthesis of 6??amino??1, 2, 3??triazolo [4, 5??c] pyridin??4 (5H) one (8??aza??3??deazaguanine) and 6??amino??1??(β??D??ribofuranosyl)??1, 2, 3??triazolo [4, 5??c] pyridin??4 (5H) …

RHB Meyer, GR Revankar, P Dan Cook…

Index: Meyer Jr.; Revankar; Cook; et al. Journal of Heterocyclic Chemistry, 1980 , vol. 17, # 1 p. 159 - 169

Full Text: HTML

Citation Number: 13

Abstract

Abstract The total synthesis of 6-amino-1, 2, 3-triazolo [4, 5-c] pyridin-4 (5H) one (8-aza-3- deazaguanine, 3) and 6-amino-1-(β-D-ribofuranosyl)-1, 2, 3-triazolo [4, 5-c] pyridin-4 (5H) one (8-aza-3-deazaguano-sine, 22) has been described for the first time by a novel base- catalyzed ring closure of 4 (5)-cyanomethyl-1, 2, 3-triazole-5 (4) carboxamide (14) and methyl 5-cyanomethyl-1-(2, 3, 5-tri-O-ben-zoyl-β-D-ribofuranosyl)-1, 2, 3-triazole-4- ...

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dimethyl 3-[(2,4-dinitrophenyl)hydrazinylidene]pentanedioate Structure

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b-D-Ribofuranose 1-acetate 2,3,5-tribenzoate Structure

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5-(cyanomethyl)-2-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]triazole-4-carboxamide Structure

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1H-1,2,3-Triazole-4-carboxylicacid,5-(cyanomethyl)-,methylester(9CI) Structure

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methyl 5-(carbamoylmethyl)-2H-triazole-4-carboxylate Structure

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4H-1,2,3-Triazolo[4,5-c]pyridin-4-one,6-amino-3,5-dihydro Structure

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4H-1,2,3-Triazolo[4,5-c]pyridin-4-one,6-amino-3,5-dihydro Structure

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