Chemical Communications 2005-03-07

First successful application of diphosphite ligands in the asymmetric hydroformylation of dihydrofurans.

Montserrat Dieguez, Oscar Pamies, Carmen Claver

Index: Chem. Commun. (Camb.) (9) , 1221-3, (2005)

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Abstract

Good enantioselectivities and excellent regioselectivities are achieved in the Rh-catalyzed asymmetric hydroformylation of 2,5- and 2,3-dihydrofuran using diphosphite ligands; whereby the backbone of the ligand is crucial to suppressing isomerization and obtaining high ee's.