A novel family of aromatic diazirines for photoaffinity labeling

…, M Hashimoto, H Kurihara, H Nakayama…

Index: Hatanaka, Yasumaru; Hashimoto, Makoto; Kurihara, Hiroko; Nakayama, Hitoshi; Kanaoka, Yuichi Journal of Organic Chemistry, 1994 , vol. 59, # 2 p. 383 - 387

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Citation Number: 113

Abstract

A series of simple methods for modifying diazirines bearing an aromatic ring has been accomplished. This first versatile approach involving direct substitution on the aromatic ring of diazirines has been achieved by means of the aromatic thallation of (alkoxypheny1) diazirines. Introduction of the thallium moiety was successfully followed by nitration, iodination, or palladium-catalyzed carbonylation to give a family of substituted ...