Synlett

P (MeNCH2CH2) 3N: an efficient catalyst for the synthesis of substituted ethyl benzofuran-2-carboxylates

BA D'Sa, P Kisanga, JG Verkade

Index: D'Sa, Bosco A.; Kisanga, Philip; Verkade, John G. Synlett, 2001 , # 5 p. 670 - 672

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Citation Number: 11

Abstract

Abstract: A superior method for the synthesis of substituted ethyl benzofuran-2-carboxylates in 80-99% yields from substituted 2-formylphenoxy ethylcarboxylates using 0.4 equiv of commercially available P (MeNCH2CH2) 3N at 70 C for 3 hours is described. Key words: benzofurans, bicyclic compounds, catalysis, cyclizations, heterocyclics