Research on Chemical Intermediates

Synthesis and antimicrobial activity of 2H-pyrimido [2, 1-b] benzothiazol-2-ones

PK Sharma, M Kumar, V Mohan

Index: Sharma, Praveen Kumar; Kumar; Mohan, Vimal Research on Chemical Intermediates, 2010 , vol. 36, # 8 p. 985 - 993

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Citation Number: 12

Abstract

Abstract 4-Phenyl-2 H-pyrimido [2, 1-b] benzothiazol-2-ones have been synthesized in quantitative yields by the reaction of 2-aminobenzothiazoles with alkynoic acid. The antimicrobial activity of the synthesized compounds was tested against bacterial species, Bacillus coagulans, Bacillus subtilis, Staphylococcus aureus, and Pseudomonas aeruginosa. The synthesized compounds have shown significant activity against ...