A new orally bioavailable dual adenosine A 2B/A 3 receptor antagonist with therapeutic potential

NJ Press, RJ Taylor, JD Fullerton, P Tranter…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 12 p. 3081 - 3085

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Citation Number: 34

Abstract

... Bioorganic & Medicinal Chemistry Letters. ... By means of novel chemistry, we have synthesised 5-heterocyclic substituted aminothiazoles, which have shown improved selectivity and affinity for the A 2B and A 3 receptors. ...