Journal of the American Chemical Society 2010-10-13

Palladium-catalyzed conversion of aryl and vinyl triflates to bromides and chlorides.

Xiaoqiang Shen, Alan M Hyde, Stephen L Buchwald

Index: J. Am. Chem. Soc. 132 , 14076, (2010)

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Abstract

The palladium-catalyzed conversion of aryl and vinyl triflates to aryl and vinyl halides (bromides and chlorides) has been developed using dialkylbiaryl phosphine ligands. A variety of aryl, heteroaryl, and vinyl halides can be prepared via this method in good to excellent yields.