Phospshoinositide 3-kinase (PI3K)/mammalian target of rapamycin (mTOR) dual inhibitors: discovery and structure–activity relationships of a series of quinoline and …

N Nishimura, A Siegmund, L Liu, K Yang…

Index: Journal of Medicinal Chemistry, , vol. 54, # 13 p. 4735 - 4751

Full Text: HTML

Citation Number: 39

Abstract

... Journal of Medicinal Chemistry. ... Department of Chemistry Research and Discovery, ‡ Department of Oncology Research, § Pharmacokinetics & Drug Metabolism, ∥ Department of Molecular Structure, and ⊥ Department of High-Throughput Screening/Molecular ...

Elucidation of a structural basis for the inhibitor-driven, ...

[Day, Jonathan P.; Lindsay, Barbara; Riddell, Tracy; Jiang, Zhong; Allcock, Robert W.; Abraham, Achamma; Sookup, Sebastian; Christian, Frank; Bogum, Jana; Martin, Elisabeth K.; Rae, Robert L.; Anthony, Diana; Rosair, Georgina M.; Houslay, Daniel M.; Huston, Elaine; Baillie, George S.; Klussmann, Enno; Houslay, Miles D.; Adams, David R. Journal of Medicinal Chemistry, 2011 , vol. 54, # 9 p. 3331 - 3347]

Palladium-catalyzed cross-coupling reactions for the synthes...

[Journal of Medicinal Chemistry, , vol. 43, # 4 p. 675 - 682]

A scalable synthesis of a 1, 7-naphthyridine derivative, a P...

[Organic Process Research and Development, , vol. 14, # 4 p. 883 - 889]