European Journal of Gastroenterology and Hepatology 1997-04-01

Tenoxicam-associated hepatic injury: a case report and review.

P Katsinelos, I Katsos, K Patsiaoura, P Xiarchos, I Goulis, N Eugenidis

Index: Eur. J. Gastroenterol. Hepatol. 9(4) , 403-6, (1997)

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Abstract

A 51-year-old woman developed jaundice while taking tenoxicam. A full evaluation, including ultrasound, computed tomography, endoscopic cholangiography and liver biopsy, confirmed the diagnosis of mixed hepatic injury. The patient's jaundice and all other liver function abnormalities normalized 1 month after she discontinued taking tenoxicam. This is the first case report of mixed hepatic injury, confirmed with biopsy, associated with tenoxicam. Tenoxicam should be considered as a potential cause of hepatic injury when other more common aetiologies have been excluded.