PRELIMINARY ANTIPROLIFERATIVE EVALUATION OF NATURAL,-SYNTHETIC BENZALDEHYDES AND BENZYL ALCOHOLS

…, K Catalan, C Gonzalez, I Montenegro…

Index: Madrid, Alejandro; Espinoza, Luis; Catalan, Karen; Gonzalez, Cesar; Montenegro, Ivan; Mellado, Marco; Werner, Enrique; Cuellar, Mauricio; Villena, Joan Journal of the Chilean Chemical Society, 2013 , vol. 58, # 3 p. 1814 - 1816

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Abstract

ABSTRACT Vanillin, o-vanillin, natural and synthetic benzaldehydes and benzyl alcohols were assessed for antiproliferative effects using different human cell lines. Benzyl alcohols were synthesized from benzaldehydes reduced with NaBH 4 in methanol solution. A new method for deprotection of ether compounds with TiCl 4 solution was achieved with better performance, than previously reported. Twenty four compounds were tested. The in vitro ...