Ophthalmology 2013-11-01

CFH and ARMS2 genetic polymorphisms predict response to antioxidants and zinc in patients with age-related macular degeneration.

CarlC Awh, Anne-Marie Lane, Steven Hawken, Brent Zanke, IvanaK Kim

Index: Ophthalmology 120(11) , 2317-23, (2013)

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Abstract

The Age-Related Eye Disease Study (AREDS) demonstrated that antioxidant and zinc supplementation decreases progression to advanced age-related macular degeneration (AMD) in patients with moderate to severe disease. We evaluated the interaction of genetics and type of nutritional supplement on progression from moderate to advanced AMD.