CuI??Catalyzed 11C Carboxylation of Boronic Acid Esters: A Rapid and Convenient Entry to 11C??Labeled Carboxylic Acids, Esters, and Amides

PJ Riss, S Lu, S Telu, FI Aigbirhio…

Index: Riss, Patrick J.; Lu, Shuiyu; Telu, Sanjay; Aigbirhio, Franklin I.; Pike, Victor W. Angewandte Chemie - International Edition, 2012 , vol. 51, # 11 p. 2698 - 2702

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Citation Number: 32

Abstract

Noninvasive imaging with positron emission tomography (PET) allows for quantitative studies of radiotracer distribution in living subjects and is increasingly used in routine clinical diagnosis, preclinical and clinical-phase drug development, and biomedical research. Novel radiotracers for imaging a variety of biological targets are continually needed to fully exploit the potential of PET. Consequently, the existence of reliable chemical methods for ...