Tetrahedron letters

gem-Dihalocyclopropane formation by iron/copper activation of tetrahalomethanes in the presence of nucleophilic olefins. Evidence for a carbene pathway

…, M Lejaye, S Oudeyer, JP Paugam, JY Nédélec

Index: Leonel, Eric; Lejaye, Michael; Oudeyer, Sylvain; Paugam, Jean Paul; Nedelec, Jean-Yves Tetrahedron Letters, 2004 , vol. 45, # 12 p. 2635 - 2638

Full Text: HTML

Citation Number: 8

Abstract

The activation of CBr4 and CCl4 by a bimetallic iron/copper couple in acetonitrile is a new, inexpensive, nontoxic and efficient procedure for gem-dibromo-and gem- dichloromethylenation of nucleophilic alkenes. This new route to gem-dihalocyclopropanes involves dihalocarbene species.