PANORAMA DU M�DECIN 2013-04-01

[Syphilis].

Nicolas Dupin, David Farhi

Index: Presse Med. 42(4 Pt 1) , 446-53, (2013)

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Abstract

Syphilis is back since 2000. Early syphilis comprises primary syphilis, secondary syphilis and early latent syphilis (less than 1 year duration). During early phases of syphilis, patients are more contagious and neurologic complications are rare. Early neurosyphilis are mostly represented by uveitis or cranial nerves lesions. Treatment of non-neurologic syphilis are based on intramusculary injection of benzathine-penicilline G: one injection in case of early syphilis, three injections in case of late syphilis. The follow-up after treatment is based on clinical evolution and the titer of VDRL. Intravenously infusion of penicillin G is the only treatment recommended for neurosyphilis.Copyright © 2013 Elsevier Masson SAS. All rights reserved.