Organic Letters 2006-07-06

Mild manganese(III) acetate catalyzed allylic oxidation: application to simple and complex alkenes.

Tony K M Shing, Ying-Yeung Yeung, Pak L Su

Index: Org. Lett. 8 , 3149, (2006)

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Abstract

Manganese(III) acetate catalyzed allylic oxidation of alkenes to the corresponding enones was investigated, showing excellent regioselectivity and chemoselectivity (functional group compatibility). Delta(5)-Steroids were transformed into bioactive Delta(5)-en-7-ones under a nitrogen atmosphere, whereas simple alkenes were converted into the corresponding enones under an oxygen atmosphere in good yields.