Bulletin of Experimental Biology and Medicine 2011-11-01

Catecholamines, α-, and β-adrenoceptors are not responsible for activation of duodenum motility induced by sympathetic nerve stimulation.

D S Sveshnikov, V M Smirnov, I L Myasnikov, M I Mongush, I A Yurasova

Index: Bull. Exp. Biol. Med. 152(1) , 5-8, (2011)

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Abstract

Stimulation of sympathetic nerve in anesthetized dogs not treated with adrenergic blockers more frequently exerted stimulating rather than inhibitory effect on duodenal motility. Blockade of α- and β-adrenoceptors with phentolamine and propranolol, respectively, did not prevent the excitatory action of the sympathetic nerve stimulation, but even potentiated this effect. The data showed that catecholamines as well as α- and β-adrenoceptors are not involved in the excitatory effect of sympathetic origin.