Angewandte Chemie International Edition

Double Duty for Cyanogen Bromide in a Cascade Synthesis of Cyanoepoxides

Z Li, V Gevorgyan

Index: Li, Zhou; Gevorgyan, Vladimir Angewandte Chemie - International Edition, 2011 , vol. 50, # 12 p. 2808 - 2810

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Citation Number: 12

Abstract

Cyanogen bromide is a versatile reagent used in organic synthesis. Under different conditions, the BrÀC bond can be cleaved in a diverse manner (Scheme 1, Modes I–IV). Thus, BrCN was shown to serve as a donor of Br+ in reactions with strongly nucleophilic organometallic reagents to provide the corresponding vinyl-or arylbromides (ModeI).[1] In the reaction with vinyltellrium bromide, cyanogen bromide acted as an equivalent of a ...