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e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

Nature

Metal-free oxidation of aromatic carbon-hydrogen bonds through a reverse-rebound mechanism

C Yuan, Y Liang, T Hernandez, A Berriochoa, KN Houk…

Index: Nature, , vol. 499, # 7457 p. 192 - 196

Full Text: HTML

Citation Number: 44

Abstract

... Journal name: Nature Volume: 499, Pages: 192–196 Date published: (11 July 2013) DOI: doi:10.1038/nature12284 ... One example is the natural product (+)-δ-tocopherol, which decreases the incidence of prostate cancer as demonstrated in a 2003 clinical trail 22 . ...

 Related Synthetic Route
1,2,3,4-Tetrahydronaphthalene Structure

119-64-2

1,2,3,4-Tetrahy...

~%

5,6,7,8-Tetrahydro-2-naphthol Structure

1125-78-6

5,6,7,8-Tetrahy...

5-Hydroxytetralin Structure

529-35-1

5-Hydroxytetralin

Indane Structure

496-11-7

Indane

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5-Indanol Structure

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5-Indanol

4-Indanol Structure

1641-41-4

4-Indanol

1-Bromo-3,5-dimethylbenzene Structure

556-96-7

1-Bromo-3,5-dim...

~%

4-Bromo-2,6-dimethylphenol Structure

2374-05-2

4-Bromo-2,6-dim...

2-Bromo-4,6-dimethylphenol Structure

15191-36-3

2-Bromo-4,6-dim...

Indane Structure

496-11-7

Indane

~%

5-Indanol Structure

1470-94-6

5-Indanol

4-Indanol Structure

1641-41-4

4-Indanol

m-Xylene Structure

108-38-3

m-Xylene

~%

2,6-Xylenol Structure

576-26-1

2,6-Xylenol

2,4-xylenol Structure

105-67-9

2,4-xylenol

4-Methylanisole Structure

104-93-8

4-Methylanisole

~%

6-Methoxy-m-cresol Structure

1195-09-1

6-Methoxy-m-cresol

5-methoxy-2-methylphenol Structure

20734-74-1

5-methoxy-2-met...

Butylbenzene Structure

104-51-8

Butylbenzene

~%

4-Butylphenol Structure

1638-22-8

4-Butylphenol

2-n-BUTYLPHENOL Structure

3180-09-4

2-n-BUTYLPHENOL

1-Bromo-3,5-dimethylbenzene Structure

556-96-7

1-Bromo-3,5-dim...

~%

4-Bromo-2,6-dimethylphenol Structure

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4-Bromo-2,6-dim...

2-Bromo-4,6-dimethylphenol Structure

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2-Bromo-4,6-dim...

3,4-Dimethoxyacetophenone Structure

1131-62-0

3,4-Dimethoxyac...

~%

Ethanone,1-(2-hydroxy-3,4-dimethoxyphenyl)- Structure

5396-18-9

Ethanone,1-(2-h...

m-Xylene Structure

108-38-3

m-Xylene

~%

2,6-Xylenol Structure

576-26-1

2,6-Xylenol

2,4-xylenol Structure

105-67-9

2,4-xylenol

1,2,3,4-Tetrahydronaphthalene Structure

119-64-2

1,2,3,4-Tetrahy...

~%

5,6,7,8-Tetrahydro-2-naphthol Structure

1125-78-6

5,6,7,8-Tetrahy...

5-Hydroxytetralin Structure

529-35-1

5-Hydroxytetralin

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Detail Synthetic Route


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