Abstract An aerobic CeCl 3· 7H 2 O/NaI-catalyzed C–H functionalization reaction was developed for the synthesis of 3-sulfenylimidazo [1, 2-a] pyridines from easily available ketones, 2-aminopyridines, and disulfides without DMSO or peroxide as an oxidant. This three-component tandem reaction process involves the formation of imidazo [1, 2-a] pyridines followed by Friedel–Crafts sulfenylation in one pot under mild conditions. Both ...
![3-methyl-2-phenylimidazo[1,2-a]pyridine Structure](https://image.chemsrc.com/caspic/071/34658-68-9.png)