Neurochemistry International 2011-01-01

Neuroprotective effects of SCM198 on 6-hydroxydopamine-induced behavioral deficit in rats and cytotoxicity in neuronal SH-SY5Y cells

Xue Ru Shi, Zhen Yi Hong, Hong Rui Liu, Yu Chen Zhang, Yi Zhun Zhu

Index: Neurochem. Int. 58(8) , 851-60, (2011)

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Abstract

Research highlights ► SCM198 (Leonurine) possessed neuroprotective potential both in vivo and in vitro. ► SCM198 exerted neuroprotective effect by inhibiting oxidative stress and apoptosis. ► We can develop therapeutic strategy for neurodegenerative diseases based on SCM198.