New England Journal of Medicine 2014-07-10

Hormone therapy in premenopausal women with early-stage breast cancer.

Hope S Rugo

Index: N. Engl. J. Med. 371(2) , 175-6, (2014)

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Abstract

Breast cancer is the most frequent cancer diagnosis in women worldwide and the most common cause of death from cancer. In the United States, 21% of breast cancers are diagnosed in women younger than 50 years of age, affecting almost 49,000 women, and this disease remains a leading cause of death.1 The most common form of breast cancer is hormone-receptor–positive disease, and the incidence of this subtype, particularly among younger women, has increased in the past decade, probably owing to changes in lifestyle factors and diet. For these reasons, improving the outcome of hormone-receptor–positive breast cancer in young women is . . .