Chemical Communications

Palladium-catalyzed deamidative arylation of azoles with arylamides through a tandem decarbonylation–C–H functionalization

C Li, P Li, J Yang, L Wang

Index: Li, Chengliang; Li, Pinhua; Yang, Jin; Wang, Lei Chemical Communications, 2012 , vol. 48, # 35 p. 4214 - 4216

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Citation Number: 35

Abstract

A highly chemo-, regio-selective, and efficient palladium-catalyzed deamidative arylation of azoles with arylamides, as an aryl metal equivalent, has been developed. The reaction proceeds smoothly to generate the corresponding products in good yields via a tandem decarbonylation–C–H activation.

~90%

~91%

~41%

~75%

~71%

~63%

~72%

~53%

~73%

~56%

~92%

~80%

~86%

~80%

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