Pediatrics 1991-02-01

Methsuximide for intractable childhood seizures.

M B Tennison, R S Greenwood, M V Miles

Index: Pediatrics 87(2) , 186-9, (1991)

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Abstract

Methsuximide was added to the therapeutic regimens of 25 children with intractable epilepsy. In 15 patients the drug was well tolerated and resulted in a 50% or greater reduction in seizure frequency. No serious or irreversible adverse effects were seen. Methsuximide is frequently overlooked and may be an effective adjunctive antiepileptic for children with intractable seizures.