The Journal of Organic Chemistry

New approaches to the synthesis of cystine peptides using N-iodosuccinimide in the construction of disulfide bridges

H Shih

Index: Journal of Organic Chemistry, , vol. 58, # 11 p. 3003 - 3008

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Citation Number: 15

Abstract

... The chemistry of disulfide bond formation is complicated in peptide synthesis, especially in multi-cystine peptides such as a ~ amin , l - ~ insulin-like ... isolation of free cystine due to the high solubility of the TFA salt of cystine in water and in most organic solvents such ... 3004 J. Org. ...