Bioorganic & Medicinal Chemistry Letters 2005-01-17

QSAR study on the antibacterial activity of some sulfa drugs: building blockers of Mannich bases.

Dheeraj Mandloi, Sheela Joshi, Padmakar V Khadikar, Navita Khosla

Index: Bioorg. Med. Chem. Lett. 15 , 405-11, (2005)

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Abstract

Sulfa drugs are building blockers of several types of Mannich bases. Consequently, the antibacterial activities of sulfa drugs are reported in this paper, which will help in explaining and understanding antibacterial activities of Mannich bases. Reported QSAR is carried out using distance-based topological indices and discussed critically on the basis of statistical parameters.