e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

Tetrahedron letters

A one-pot synthesis of ibuprofene involving three consecutive steps of superbase metalation

F Faigl, M Schlosser

Index: Tetrahedron Letters, , vol. 32, # 28 p. 3369 - 3370

Full Text: HTML

Citation Number: 28

Abstract

Page 1. Tetr&edron Letters, Vo1.32. No.28. pi 3369-3374 1991 Printed in Great Britain 00404039191 $3.00 + .oo Pergamon Press plc A ONE-POT SYNTHESIS OF IBUPROFENE INVOLVING THREE CONSECUTIVE STEPS OF SUPERBASE METAIXI'ION ...

2-Bromobutane Structure

~%

1-Hexene, 3,4-dimethyl- Structure

1-Hexene, 3,4-d...

(Z)-5-Methyl-2-heptene Structure

(Z)-5-Methyl-2-...

p-Xylene Structure

~%

Ibufenac Structure

Carbon dioxide Structure

1-methyl-4-isobutylbenzene Structure

1-methyl-4-isob...

~%

Ibufenac Structure

p-Xylene Structure

methyl iodide Structure

~%

4-Ethyltoluene Structure

p-Xylene Structure

~%

Ibuprofen Structure

4-Ethyltoluene Structure

~%

Ibuprofen Structure

1-methyl-4-isobutylbenzene Structure

1-methyl-4-isob...

~%

Ibuprofen Structure

Carbon dioxide Structure

1-Ethyl-4-Isobutylbenzene Structure

1-Ethyl-4-Isobu...

~%

Ibuprofen Structure

Ibufenac Structure

methyl iodide Structure

~%

Ibuprofen Structure

An Alkyl??Aluminium Promoted Stereospecific Addition to Viny...

[Helvetica Chimica Acta, , vol. 56, # 4 p. 1192 - 1198]

An Alkyl??Aluminium Promoted Stereospecific Addition to Viny...

[Helvetica Chimica Acta, , vol. 56, # 4 p. 1192 - 1198]