Tetrahedron letters

Solvent-induced hydrogen tunnelling in ascorbate proton-coupled electron transfers

A Karković, CJ Brala, V Pilepić, S Uršić

Index: Karkovic, Ana; Brala, Cvijeta Jakobusic; Pilepic, Viktor; Ursic, Stanko Tetrahedron Letters, 2011 , vol. 52, # 15 p. 1757 - 1761

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Citation Number: 7

Abstract

Quantum-mechanical hydrogen tunnelling is of remarkable significance for chemistry and biochemistry. 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18 and 19 The role of hydrogen tunnelling in such fundamental chemical reactions as hydrogen transfers is well documented 3, 4, 17, 18 and 19 and enzymatic C–H activation has been shown to take place via tunnelling. 2, 3, 4, 5, 6, 7, 8, 9, 10, 13, 14 and 16 Many non-enzymatic H-transfer ...