Journal of Analytical Toxicology 1984-01-01

Arylhydroxy metabolites of cocaine in the urine of cocaine users.

R M Smith

Index: J. Anal. Toxicol. 8(1) , 35-7, (1984)

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Abstract

The major arylhydroxy metabolite of cocaine in human urine was identified as 4'-hydroxybenzoylecgonine methyl ester by comparison of mass spectral and relative gas-liquid chromatography retention time data of metabolites in patient samples with those of the three synthesized positional isomers. The 3'-hydroxy isomer was also identified in most samples, but its concentration varied widely from sample to sample.