Tetrahedron letters

Wittig reactions in water. Synthesis of new water-soluble phosphonium salts and their reactions with substituted benzaldehydes

MG Russell, S Warren

Index: Russell, Matthew G.; Warren, Stuart Tetrahedron Letters, 1998 , vol. 39, # 43 p. 7995 - 7998

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Citation Number: 37

Abstract

We report the synthesis of new phosphonium salts which are soluble and stable in basic aqueous solution. The Wittig reactions of these phosphonium salts with substituted benzaldehydes in aqueous sodium hydroxide are discussed. These reactions exclude the use of any organic solvents and the products are isolated by a simple filtration.